Child-Turcotte-Pugh scoring for cirrhosis severity, surgical risk and 1- and 2-year survival estimates. Calculations run locally in your browser.
Disclaimer: The Child-Pugh score is a prognostic tool, not a diagnosis. It does not capture renal dysfunction, hyponatraemia or variceal bleeding — for transplant prioritisation, MELD-Na has largely replaced Child-Pugh. Surgical and TIPS decisions must integrate the full clinical picture (MELD, platelets, hepatic venous pressure gradient, frailty, comorbidities) and senior hepatology input.
Child-Pugh uses 2 subjective parameters (ascites, encephalopathy) and 3 lab values; MELD uses only objective lab values (bilirubin, INR, creatinine; MELD-Na adds sodium). MELD-Na is the standard for liver-transplant prioritisation in most allocation systems and predicts 90-day mortality better than Child-Pugh. Child-Pugh remains very useful at the bedside for quick severity grading, surgical-risk discussion and TIPS candidacy.
In primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), bilirubin is chronically elevated out of proportion to other liver function. Pugh's original 1973 paper recommended raising the bilirubin cut-offs to <4 / 4–10 / >10 mg/dL in these conditions to avoid over-classifying patients. The other four parameters remain unchanged.
Mansour et al. (1997) and later series report 30-day post-operative mortality of roughly 10% in Child A, 30% in Child B and 75–82% in Child C for abdominal surgery. Class C is generally considered a relative contraindication to non-transplant elective surgery; class B requires careful pre-operative optimisation (ascites, encephalopathy, nutrition, INR) and intensive perioperative support. For ambulatory cholecystectomy and hernia repair, current guidance also factors in MELD <10.
No. In ACLF the prognosis is driven by extrahepatic organ failures (renal, circulatory, respiratory, cerebral). Use the CLIF-C ACLF score or AARC score (commonly used in India) for ACLF severity. Child-Pugh underestimates short-term mortality in this group.
Many drug labels (especially DOACs, statins, sorafenib, some antifungals and antibiotics) provide dosing guidance keyed to Child-Pugh class. For these, use the score as a prescribing reference. Note that "use with caution" or "avoid in Child-Pugh C" is a label-level statement — pharmacokinetic data in advanced cirrhosis are often limited, so individualise based on therapeutic-drug monitoring where possible.
Survival estimates from Pugh (1973) and Infante-Rivard (1987). Surgical mortality estimates from Mansour et al. (1997). Always defer to your hepatology and surgical team's local protocols.
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